Guidelines

In each case, a disease map is designed while taking into account the goals and objectives of a particular project, specifics of disease conditions and disease subtypes. Here we propose a set of guidelines for a disease map construction and define some concepts that are derived from our collective experience and that might be helpful for developing a new disease map.

Steps

  1. Form a panel of domain experts: leading researchers, clinicians and biologist, with experience in the field of this particular disorder.
  2. Define the scope of a disease map. What are the disease hallmarks? What are the key modules? What levels of granularity should be included?
  3. Develop an overview map and start determining the content in close communication with the domain experts.
  4. Develop a draft version reusing information from other disease maps and pathway databases.
  5. Develop a comprehensive version.

These steps can be done in parallel.

Proposed milestones