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About

The Disease Maps Project as a large-scale community effort was initiated by the Luxembourg Centre for Systems Biomedicine, the European Institute for Systems Biology and Medicine and the Institut Curie.

Principal Investigators

Charles Auffray Charles Auffray, PhD
European Institute for Systems Biology and Medicine, Lyon, France
Research Director at CNRS, Founding Director of the EISBM
Reinhard Schneider Reinhard Schneider, PhD
University of Luxembourg, Luxembourg
Head of Bioinformatics Core, Luxembourg Centre for Systems Biomedicine
Emmanuel Barillot Emmanuel Barillot, PhD
Institut Curie, Paris, France
Director of the U900 Institut Curie/INSERM/Ecole des Mines ParisTech

Project Leaders

The leaders of the Disease Maps Project develop and refine the concept of disease maps, coordinate the activities of the community effort, help initiating new maps, advise on best practices and offer guidelines.

Alexander Mazein Alexander Mazein, PhD
European Institute for Systems Biology and Medicine, Lyon, France
Senior Researcher
Marek Ostaszewski Marek Ostaszewski, PhD
University of Luxembourg, Luxembourg
Researcher, Luxembourg Centre for Systems Biomedicine
Inna Kuperstein Inna Kuperstein, PhD
Institut Curie, Paris, France
ACSN Project Coordinator, Computational Systems Biology of Cancer group

Scientific Advisory Board

The Scientific Advisory Board is composed of scientists with expertise in large-scale systems biology and translational medicine projects. The board provides guidance regarding the goals and the roadmap for the Disease Maps Project.

The list of the Scientific Advisory Board members is being confirmed.

Acknowledgements

We would like to thank Rudi Balling, the Director of the Luxembourg Centre for Systems Biomedicine for his longstanding and enthusiastic support to the concept of disease maps. He is one of the key people that helped to catalyse the Disease Maps Project.

Most of the published disease maps were developed in collaboration with the Systems Biology Institute, Tokyo, Japan (Mizuno et al., 2012, PMID 22647208; Matsuoka et al., 2013, PMID 24088197; Fujita et al., 2014, PMID 23832570; Kuperstein et al., 2015, PMID 26192618). We would like to underline the role of Prof. Hiroaki Kitano in pioneering the process description representation of signalling networks and initiating first comprehensive disease-relevant extensive reconstructions of signalling pathways (Oda et al., 2005, PMID 16729045; Oda and Kitano, 2006, PMID 16738560; Caron et al., 2010, PMID 21179025).

Funding

The Disease Maps Project is funded in part by IMI eTRIKS n°115446 (eTRIKS, European Translational Information and Knowledge Management Services)