Projects

   Disease maps for specific diseases
   Cross-disease projects
   Adverse outcome maps for immunotoxicology

The Disease Maps Community consolidates efforts focused on describing disease mechanisms. We aim to progress together through advancing technological solutions, sharing resources and best practices. New contributors are very welcome: please propose a new disease map or join one of the existing projects. Project progress status:

☆☆☆☆☆ Initiated/funded ★☆☆☆☆ Active development ★★☆☆☆ Available for exploration online

★★★☆☆ Published ★★★★☆ Maintained and improved ★★★★★ Applications demonstrated

Disease maps for specific diseases

This section lists projects focused on specific diseases. The list is organised according to the progress status of the projects.

COVID-19, Parkinson’s disease, cancer, rheumatoid arthritis, asthma, sarcopenia, cystic fibrosis, heart failure, atherosclerosis, osteoarthritis, Sjogren’s syndrome, diabetic kidney disease, atopic dermatitis, psoriasis, liver steatosis, cholestasis

	Resource: COVID-19 Disease Map Contact: Marek Ostaszewski, University of Luxembourg, Belvaux, Luxembourg Publications: PubMed
	Resource: Parkinson's Disease Map Contact: Marek Ostaszewski, University of Luxembourg, Belvaux, Luxembourg Publications: PubMed
	Resource: Atlas of Cancer Signalling Network Contact: Inna Kuperstein, Institut Curie, Paris, France Publications: PubMed
	Resource: Rheumatoid Arthritis Map Contact: Anna Niarakis, Paul Sabatier University - Toulouse III, Toulouse, France Publications: DOI
	Resource: AsthmaMap Contact: Alexander Mazein, University of Luxembourg, Belvaux, Luxembourg Publications: PubMed
	Resource: Sarcopenia Map Contact: Matti Hoch, University of Rostock, Rostock, Germany Publications: PubMed
	Resource: CyFi-MAP Contact: Catarina Pereira, University of Lisbon, Lisbon, Portugal Publications: PubMed
	Resource: CardioMap Contact: Nikolaus Berndt, Charité – Universitätsmedizin Berlin; Irina Balaur, University of Luxembourg | Publications: PubMed
	Resource: Atherosclerosis Map Contact: Steven Watterson, Ulster University, Derry, Northern Ireland, UK Publications: PubMed | Model: BioModels
	Resource: KneePainMap Contact: Bernd Seilheimer, Heel GmbH, Germany
	Resource: Sjogren Map Contact: Sacha E Silva-Saffar, University of Evry, University of Paris-Saclay, France
	Resource: Diabetic Kidney Disease Map Contact: Farnoush Kiyanpour, Isfahan University of Medical Sciences, Iran
	Resource: Atopic Dermatitis Map Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg
	Resource: Psoriasis Map Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg
	Resource: Liver Lipid Metabolism Physiological Map Contact: Luiz Ladeira, University of Liège, Liège, Belgium
	Resource: Liver Bile Secretion Physiological Map Contact: Luiz Ladeira, University of Liège, Liège, Belgium

Cross-disease projects

This section includes projects that focus on shared mechanisms of two or more diseases, interactions between two or more diseases, or broader aspects applicable to many diseases.

	Resource: Atlas of Inflammation Resolution Contact: Matti Hoch, University of Rostock, Rostock, Germany Publications: PubMed
	Resource: Neural Tube Closure Physiological Map Contact: Alessio Gamba, University of Liège, Liège, Belgium Publications: PubMed
	Resource: SYSCID Map Diseases: IBD, rheumatoid arthritis and systemic lupus erythematosus Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg Publications: DOI
	Resource: ImmUniverse Map Diseases: ulcerative colitis, atopic dermatitis Contact: Marcio Luis Acencio, University of Luxembourg, Belvaux, Luxembourg
	Resource: Nephron Physiological Map Diseases: kidney crystallopathy, tubular necrosis Contact: Alessio Gamba, University of Liège, Liège, Belgium
	Resource: Brain Development Physiological Map Contact: Luiz Ladeira, University of Liège, Liège, Belgium

Adverse outcome maps for immunotoxicology

This section includes maps that describe mechanisms of adverse effects of various treatments and are based on the adverse outcome pathway (AOP) concept in toxicology.

	Resource: CAR T cell AOP Map Contact: Alexander Mazein, University of Luxembourg, Belvaux, Luxembourg Publications: Preprint
	Resource: Cytokine Release Syndrome Map Contact: Alexander Mazein, University of Luxembourg, Belvaux, Luxembourg