Adult neurogenesis

The Cognitive Resilience Map


Adult neurogenesis in the hippocampus provides a source of cellular plasticity that appears to contribute to a 'cognitive reserve' helping to buffer against cognitive decline even in cases of neuronal loss. The process of adult neurogenesis, the generation of new neurons from a neuronal stem cell pool, involves multiple cell types and sub-processes each of which is sensitive to a different combination of environmental influences. The Cognitive Resilience Map project aims to collate the molecular, cellular, behavioural and environmental factors associated with adult neurogenesis into a formal interaction model to aid future research in the field.

Development Team

Rupert Overall Rupert Overall, PhD
German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany
Platform Leader, Cognitive Resilience Map


The start-up phase of the Cognitive Resilience Map is funded by the Helmholtz Network of Excellence.