Paris

The 3rd Disease Maps Community Meeting (DMCM2018) is hosted by the Computational Systems Biology of Cancer group, Institut Curie.

Key dates

Abstract submission deadline: 21 April 2018
Decision on abstract selection: 1 May 2018
Registration deadline: 21 May 2018
DMCM2018: 21-22 June 2018

Objectives

The objective of the 3rd DMCM is to consolidate efforts around the disease map projects and extend the Disease Maps Community. The 3rd DMCM will expose progress of the projects from the Disease Maps Community and beyond. The representative examples of network maps generation, their applications for disease data analysis, disease comorbidity, drug response prediction, advances in tools development and modelling approaches will be presented.

Topics

Among others, the following topics will be discussed: biocuration of prior knowledge related to different human diseases; creation and maintenance of disease network maps following common standards; sharing sub-maps with mechanisms implemented into different human diseases; providing technical solutions for network maps complexity management, mathematical modelling of maps and web-tools for explorations in maps. Topic-specific roundtable discussions will be organised to identify bottleneck problems and ways to overcome them.

Hands-on tutorials

Part of the meeting will be dedicated to demos and hands-on tutorials on major tools supporting the disease maps.

Preliminary programme

21 June

Meeting Opening
A disease map for the blood pressure and glomerular filtration regulatory network on which antihypertensive and analgesic drugs act
Francisco J. Lopez Hernandez, University of Salamanca, Salamanca, Spain
Semi-automatic generation of disease maps: focus on asthma
Alexander Mazein, European Institute for Systems Biology and Medicine, Lyon, France
Update on regulated cell death and immune maps application for disease data analysis
Maria Kondratova and Cristobal Monraz, Institute Curie, Paris, France
TBA
Feng He, Luxembourg Institute of Health, Luxembourg, Luxembourg

Coffee break

PD map applications
Stephan Gebel, Luxembourg Centre for Systems Biomedicine, Luxembourg, Luxembourg
Application of disease maps to rare diseases: as muscular dystrophies
Cecilia Jimenez Mallebrera, Hospital Sant Joan de Deu, Barcelona, Spain
Towards cystic fibrosis disease map modelling
Catarina Pereira and Andre Falcao, University of Lisbon, Lisbon, Portugal
Talks from selected abstracts
Invited talk: Wikipathways: Curation, visualzation and analysis of biological pathways
Martina-Summer Kutmon Maastricht University, Maastricht, the Netherlands

Lunch

Hands-on tutorials (two rounds of three parallel sessions)

MINERVA: data analysis on maps
Marek Ostaszewski, Luxembourg Centre for Systems Biomedicine, Luxembourg, Luxembourg
Constructing and visualizing pathways with web-based SBGN editor Newt
Ugur Dogrusoz, Bilkent University, Ankara, Turkey
COBRA toolbox: flux balance analysis on metabolic networks
Ronan Fleming, Luxembourg Centre for Systems Biomedicine, Luxembourg, Luxembourg
Coffee break
rROMA: a tool for module activity calculation from omics data and networks
Luca Albergante, Institute Curie, Paris, France
From interaction maps to dynamical models with Cell Collective platform
Tomas Helikar, University of Nebraska-Lincoln, Lincoln, United States

Project manager's discussion

Dinner

22 June

Computational systems biology approach for the study of rheumatoid arthritis: from a molecular map to a dynamical model
Anna Niarakis, Universite d' Evry Val d' Essonne, Evry Val d' Essonne, France
Parameter estimation of the asthma disease map
Thomas S. Ligon, Ludwig-Maximilians-Universitat, Munich, Germany
Jan Hasenauer, Helmholtz Zentrum Munchen, Munich, Germany
Environmental cheminformatics
Emma Schymanski, Luxembourg Centre for Systems Biomedicine
Share FAIR – Data Management and Standards for Systems Medicine
Martin Golebiewski, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany

Coffee break

TBA
Nicolas Le Novere, Babraham Institute, Babraham, United Kingdom
Talks selected from abstracts
Invited talk: Reactome multi-scale pathway visualization
Henning Hermjakob, Molecular Systems services EMBL-EBI, Cambridge, United Kingdom

Lunch

Talks selected from abstracts
Thematic discussion groups (suggested topics):
Tools for maps generation
Applications of disease map in research and clinics: what is missing to close the gap?
Maps to models: curation standards to allow easy transformation of networks into executable models
Maps' complexity management approaches
Diseased vs healthy pathway representations: how different they are?

Concluding remarks, suggestion of topics for next workshop

Abstract submission

Submit abstracts (up to 400 words) via the submission link for oral presentations and/or posters. Indicate 4 keywords to allocate it into the suitable session.

Registration

The registration is free, but mandatory. Fill in the registration form here.

Location

Batiment de biologie du developpement et cancer (BDD building)
11 rue Pierre et Marie Curie
75005, Paris
France

Travel

Coming soon

Accommodation

Recommended hotels:

Les Jardins Du Luxembourg
5 Impasse Royer-Collard, 75005 Paris, France

Hotel Elysa-Luxembourg
6 Rue Gay Lussac, 75005 Paris, France

Hotel du Brésil
10, rue Le Goff, 75005 Paris, France

Hotel Michelet Odeon
6 Place De L Odeon, 75006 Paris, France

Hotel de l'Avenir
65 rue Madame, 75006 Paris, France

Hôtel Des Mines
125 Bd Saint Michel, 75005 Paris, France

Contact

disease-maps-coord@googlegroups.com

Organisers

Computational Systems Biology of Cancer group, Institut Curie:
Emmanuel Barillot
Maria Kondratova
Inna Kuperstein
Cristobal Monraz
Andrei Zinovyev

Disease Maps Project coordinators

Alexander Mazein
Marek Ostaszewski
Inna Kuperstein
Andrei Zinovyev
Reinhard Schneider
Emmanuel Barillot
Rudi Balling
Charles Auffray